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21c Museum Hotel St. Louis

St. Louis, United States

Exclusive Five Star
Alliance Perks

SAVE $225+
  • Breakfast Daily
  • $50 F&B Credit
  • VIP Status
  • WiFi
  • Upgrade
  • Early Check-in

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21c Museum Hotel St. Louis
Opened in 2023, the 21c Museum Hotel St. Louis brings a luxury boutique hotel and contemporary art museum to downtown St. Louis, restoring the YMCA building located at 1528 Locust Street, walking distance to downtown attractions and nightlife. The hotel will feature a Free Contemporary Art Museum with over 13,000 sq. ft. of exhibition space, open 7 days a week, 365 days a year – free of charge. As well as 173 spacious guest rooms; Two 21c Suites; Two Food & Beverage options; Unique meeting and event spaces to accommodate groups of various sizes including a 4,200 sq. ft. Main Gallery for weddings, private events, and board meetings; Athletic & Swim Club available to hotel guests and members; Valet Parking; and 21c Museum Shop.

Exclusive Perks for 21c Museum Hotel St. Louis

Upgrade, $100, Breakfast and More in St. Louis

SAVE $225+

21c Museum Hotel St. Louis is a 173-room boutique hotel that features an art museum surrounded by meeting and event space showcasing rotating curated exhibitions. Amenities include a beautiful fitness room and spa with a steam room, full size pool, sauna, whirlpool, and treatment rooms. Idol Wolf and Good Press Café are available for your dining pleasures!

Guests making reservations through Five Star Alliance under the "Five Star Signature Package" or "Five Star Signature Suites & Villas" will also receive the following amenities:

  • Breakfast Daily
  • $50 F&B Credit
  • VIP Status
  • WiFi
  • Upgrade
  • Early Check-in
  • Late Check-out
Terms and Conditions
Reservations must be made through Five Star Alliance under the “5 Star Signature Package." Full breakfast is provided for up to two guests daily. A $50 food and beverage credit is included, once per room, per stay. Upgrade, early check-in and late check-out are subject to availability at time of check-in and departure.


Hotel Address:
  • 21c Museum Hotel St. Louis
  • 1528 Locust Street
  • St. Louis, MO 63103
  • United States

Location Summary
The hotel is located in the heart of downtown St. Louis, a short walk from the City Museum and CITYPARK stadium.
Banquets & Meetings
Space is available for private parties of 10-280 people, with catering provided by Idol Wolf’s culinary team.
Meeting Space
With over 14,000 square feet of art-filled exhibition and event space, 21c St. Louis features a wide range of spaces – many with cutting edge audiovisual technology. 21c is the perfect venue for board retreats, executive meetings, cocktail gatherings, reception dinners, charitable events, intimate weddings or any other special occasion.
Fine Dining On Site
Inspired by the rich culinary traditions of Spain, the team at Idol Wolf takes a playful approach to tapas style dining by combining local and seasonal ingredients with classic Iberian sensibilities. Welcoming and serving as a communal meeting place for hotel guests and downtown residents alike, Good Press is downtown St Louis’s next favorite café.
Fitness Center
Wellness center with lap pool, steam, sauna, fitness and movement studios.
Pool Indoor
Historic pool.
Spa Facility
Located in a historic building in St. Louis once used as a YMCA, Locust Street Athletic and Swim Club pays homage to its roots and reimagines the meaning of fitness and wellness. With personal and group training, swim lessons, and spa services, we offer members and guests a modernized approach to traditional methods of movement and recovery.

Hotel Amenities
  • - Banquets & Meetings
    - Meeting Space
    - Disabled Access
    - Executive Retreat
    - Fine Dining On Site
    - Fine Dining Nearby
    - Fitness Center
    - High Speed Internet
    - Pets Allowed
    - Pool Indoor
    - Spa Facility
Available Activities
  • - Hiking
    - Shopping